UJI AKTIVITAS DEODORANT SPRAY EKSTRAK ETANOL DAUN KITOLOD (Isotoma longiflora (L.) C. Presl) TERHADAP BAKTERI Staphylococcus aureus
Keywords:
Deodorant Spray, Leaf Spray, Isotoma longiflora, Antibacterial, Staphylococcus aureus.Abstract
This study aims to determine the effectiveness of ethanol extract of cytolod leaves (Isotoma longiflora (L.) C. Presl) formulated in spray deodorant preparations as an antibacterial against Staphylococcus aureus. The extraction of cytolod leaves is carried out by the maceration method using 96% ethanol solvent. Spray deodorant preparations are made in three different extract concentrations, namely 3% (F1), 5% (F2), and 8% (F3), with positive control using commercial deodorant (AXE) and negative control in the form of a base preparation without extract. Antibacterial effectiveness testing was carried out using the suction diffusion method. The results of the physical evaluation showed that all formulas met the requirements of organoleptic, pH, clarity, viscosity, drying time, sprayability, and did not cause irritation to the skin. The results of the antibacterial activity test showed that the higher the concentration of the extract, the larger the barrier zone formed. Formulas with a concentration of 8% (F3) show the most effective inhibition activity with an average inhibition zone diameter of 15.73 mm, which belongs to the strong category.
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References
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Arifin, A., Djide, N., & Iskandar, M. (2024). Identifikasi Senyawa Dan Uji Aktivitas Antibakteri Formulasi Sediaan Gel Ekstrak Etanol Daun Kitolod (Isotoma Longiflora L.) Terhadap Bakteri Staphylococcus Aureus. Jurnal Farmamedika (Pharmamedica Journal), 9(1), 131–140. https://doi.org/10.47219/ath.v9i1.282
Dewi IS, Septawati T, Rachma FA. Skrining Fitokimia Ekstrak Etanol Kulit dan Biji Terong Belanda ( Solanum betaceum Cav.). Pros Semin Nas UNIMUS. 2021;4:1210–8.
Hamka, H. N., Zahran, I., & Amri, R. (2024). Formulasi dan Uji Aktivitas Antibakteri Deodoran Spray Alami Kombinasi Ekstrak Daun Senggani (Melastoma malabathricum L.) dan Daun Bidara (Ziziphus mauritiana L.). Jurnal Mandala Pharmacon Indonesia (JMPI), 10(1), 144–157. https://doi.org/10.35311/jmpi
Hidayati, N., & Budiman, H. (2024). Uji Aktivitas Antibakteri Deodorant Spray Tea Tree Oil ( Melaleuca alternifolia ) terhadap Staphylococcus aureus ( Antibacterial Activity Test of Tea Tree Oil ( Melaleuca alternifolia ) Deodorant Spray against Staphylococcus aureus ). 06(01).
Kurniawan, K., Kusumasary, D. A., Estikomah, S. A., & Marfu’ah, N. (2024). Formulasi sediaan deodoran spray ekstrak daun sirih merah (Piper crocatum Ruiz&Pav) dengan variasi alum (tawas). Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy, 7(2), 1–10. https://doi.org/10.21111/pharmasipha.v7i2.10665
Lestari, S., Septiyani, B. N., Proklamasi Ningsih, E., & Hernayanti, H. (2024). Kandungan Flavonoid dan Aktivitas Antioksidan Kitolod (Hippobroma longiflora L.) pada Ketinggian Tempat Tumbuh Berbeda. LenteraBio : Berkala Ilmiah Biologi, 13(2), 212–218. https://doi.org/10.26740/lenterabio.v13n2.p212-218
Nurhaini, R., Arrosyid, M., & Putri, H. (2022). Formulation and Test of Antibacterial Activity of Deodorant Cream with Variations of Ylang Ylang Flower Essential Oil (Cananga odorata var. Macrophylla) as a Body Odor Remover. Journal of Pharmaceutical Sciences, 13(1), 20–30.
Permana, A., Aulia, S. D., Azizah, N. N., Rohdiana, T., Suci, S. E., Izzah, I. N. L., Agustin, A. N., & Wahyudi, S. A. (2022). ARTIKEL REVIEW : FITOKIMIA DAN FARMAKOLOGI TUMBUHAN KITOLOD (Isotoma longiflora Presi). Jurnal Buana Farma, 2(3), 22–35. https://doi.org/10.36805/jbf.v2i3.547
Retno, M. (2021). Uji Efek Pemberian Antibakteri ekstrak Daun Kitolod (Isotoma Longiflora (L) Presl.) terhadap Staphylococcus Aureus. Jurnal Medika Hutama, 2(4), 1084–1087. http://jurnalmedikahutama.com
Romdani, N. A., & , Multazam, B. A. A. M. (2024). QUALITY OF HAND SOAP WITH ADDITION KITOLOD LEAF EXTRACT (Isotoma longiflora (L.) C. Presi.). Jurnal Kimia & Pendidikan Kimia, 6(1), 54–61. https://doi.org/10.20414/spin.v6i1.8879
Rowe, R.C., Sheskey, P.J. 2009 Handbook of Pharmaceutical Excipients Sixth Edition.
Saerang, M.F., Edy, H.J. and Siampa, J.P. (2023) ‘Formulasi Sediaan Krim Dengan Ekstrak Etanol Daun Gedi Hijau (Abelmoschus manihot L.) Terhadap Propionibacterium acnes’, Pharmacon, 12(3), pp. 350–357.
Samsi, A. S. (2019). Formulation and Antibacterial Activity Test of Deodorant Spray Ethanol Extract of Ambon Banana Peel ( Musa Paradisiaca Var . Sapientum L .) Against the Growth of Staphylococcus Aureus Bacteria. 1(1), 2051–2062.
Sani, L., M., M.,Subaidah, W., A., Andayani., Y. (2021). Formulation and Evaluation of Physical Characteristics of Bay Leaf (Syzygium polyanthum) Ethanol Extract Gel Preparation. Sasamabo Journal of Pharmacy, 2(1).
Setiyowati, H., Lakshmi Ramayani, S., Katolik Mangunwijaya, P., Gajahmada No, J., Tengah Indonesia, J., Kesehatan Kementerian Kesehatan Surakarta, P., & Kesatrian No, J. (2022). POTENSI GEL HAND SANITIZER EKSTRAK DAUN KITOLOD (Isotoma longiflora L.) SEBAGAI ANTIBAKTERI TERHADAP BAKTERI Staphylococcus aureus Potency of Gel Hand Sanitizer Kitolod (Isotoma longiflora L.) Leaves Extract As Antibacterial Against Staphylococcus aureus. 2(1), 8–13.
Siahaan, A. W., Medan, U. N., Ivani, T. A., Medan, U. N., Rahmah, J. A., Medan, U. N., Sianipar, P. F., & Medan, U. N. (2024). PENGARUH DEODORANT NIVEA TERHADAP PRESEPSI DIRI DAN KEPERCAYAAN DIRI PADA MAHASISWA / I FAKULTAS. 1(4), 418–425.
Xie Y, Yang W, Tang F, Chen X, Ren L. Antibacterial Activities of Flavonoids: Structure-Activity Relationship and Antibacterial Mechanism. Curr Med Chem 2023; 22(1):132-49. https://doi.org/10.2174/09298673216 66140916113443
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05/11/2026
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