• Fazidah Aguslina Siregar Universitas Sumatera Utara
  • Tri Makmur Universitas Islam Sumatera Utara
Keywords: Lipids, metabolism, cholesterol


Lipids are a group of heterogeneous compounds related to fatty acids and are stored in the body as energy producers. Lipids consist of simple lipids (fats, waxes), lipid mixtures (phospholipids, glycolipids) and lipid derivatives (fatty acids, glycerol and steroids). Lipid As an important food element because in addition to having high energy, also because vitamins are fat soluble. Lipids affect the utilization of fat in the body. While fat functions as a heat insulator in subcutaneous tissue and an electrical insulator that allows rapid propagation of depolarization waves along the myelinated nerves. High fat content in nerve tissue. The combination of fat and protein (lipoprotein) is an important element and functions as a means of transporting lipids in the blood. Lipid metabolism consists of catabolism and anabolism, and includes triglyceride metabolism, cholesterol metabolism and lipoprotein metabolism. Abnormalities in lipid metabolism are the underlying cause of atherosclerosis which is a risk factor for coronary heart disease and stroke. Knowledge of the role and metabolism of lipids in health is important in understanding biomedical problems.


Adam, J.M. (2009). Buku Ajar Ilmu Penyakit Dalam Jilid III Edisi V. Jakarta: Balai Penerbit FKUI.
Aminuddir, P. (1992). Biokimia Nutrisi dan Metabolisme. Edisi Pertama Jakarta: Universitas Indonesia, p. 9-80.
Andrianto, P. (1996). Fisiologi Manusia dan Mekanisme Penyakit, Cetakan V. Jakarta: EGC, p. 623-9.
Geoffrey, L.Z., William, W.P., & Dennis, E.V. (1995). Principles of Biochesmistry. America: WM C. Boown Publishers, p. 459 - 73.
Guvlon, A.C. (1997). Fisiologi Kedokteran Edisi 9. Jakarta: EGC, p. 1086 - 88.
Lewis, B. (1967). The Hyperlipidaemias Clinical End Laboratory Practice. London: Oxford, p. 1-15.
Mader, S., & Windelspecht, M. (2002). Human Biology, 7ed. New York: MC Graw Hill, p. 29.
Mahan, L.K., & Stump, S.E. (1996). Food, Nutrition, Diet Therapy 9ed. Philadelpia: W.B Saunders Company, p. 49- 61.
Murray, R.K., Branner, D.K., Mayes, P.A., Rod, & Well, V.W. (2000). 1 larper's Biochemistry 29J, Now York: MC Graw Hill, p.160-71.
Wijaya, A. (1990). Gangguan Metabolisme Lemak Dan Penyakit Jantung Koroner: Seri Lipid 01. Jakarta: Program Pustaka Prodia, p. 1-31.