FORMULASI DAN UJI AKTIVITAS ANTI BAKTERI SEDIAAN SALEP EKSTRAK ETANOL DAUN SIRIH CINA (peperomia pellucida) TERHADAP BAKTERI Staphylococcus Aureus

FORMULASI DAN UJI AKTIVITAS ANTI BAKTERI SEDIAAN SALEP EKSTRAK ETANOL DAUN SIRIH CINA (peperomia pellucida) TERHADAP BAKTERI Staphylococcus Aureus

  • Rika Puspita Sari Institut Kesehatan Deli Husada
Keywords: Antibacterial activity, Chinese betel leaf Staphylococcus aureus

Abstract

Chinese betel leaf (Peperomiapellucida) is one among the wild herbaceous plants belonging to the Piperaceae family which is employed as a natural medicine. The study's goal was to determine the antibacterial activity of an ethanol extract of Chinese betel leaf ointment against Staphylococcus aureus, as well as the optimal concentration. The test of the study was administered by the diffusion method using disc paper. The results of the characterization examination of Chinese betel leaf simplicia powder obtained water soluble extract content of 64.58%, ethanol soluble extract content of 24.95%, total ash content of three 3.2%, 5.9 % water of content and 0.28% acid insoluble ash content of and Simplisia contains alkaloids, flavonoids, tannins, and saponins. Staphylococcus aureus obtained a degree of 8% with a diameter of 16.81, the diameter of the inhibition zone of the Chinese betel leaf ethanol extract against. The ethanol extract of Chinese betel leaf exhibits antibacterial action against Staphylococcus aureus, according to the findings of the study.

Keywords: Antibacterial activity, Chinese betel leaf Staphylococcus aureus

Downloads

Download data is not yet available.

References

Aisyah, F., Nisa, M. dan Rezki, R. (2019). Teknologi Sediaan Farmasi. ISB : 978-623-209-343-0. Yogyakarta : DEEPUBLISH. Halaman : 87, 437
Ansel, H. 1989. Pengantar Bentuk Sediaan Farmasi Edisi ke-4. UI Press, Jakarta.
Anief, M. (1986). Ilmu farmasi. Jakarta:Ghalia Indonesia. Halaman 61
Alfinda (2008) Metode Fitokimia. Terbitan II. A.b. Kosasih Padmawinata. ITB, Bandung.
Brooks,J.S.Butel.,S.A.Morse. (2007) Mikrobiologi Kedokteran. Salemba Medika,Jakarta.
Dalimartha, S. 1999. Atlas Tumbuhan Obat Jilid I. Trubus Agriwidya,Jakarta.
Depkes, RI. (1995). Farmakope Indonesia. Edisi IV. Jakarta: Depkes RI. Halaman: 970,1112.
Depkes RI.(1995) Materia Medika Indonesia V. Jakarta: Departemen Kesehatan Republik Indonesia. 1989.
Harbone, J.B.1996. Metode Fitokimia. Terbitan II. A.b. Kosasih Padmawinata. ITB, Bandung.
Jawetz, E,J. Melnick., Adelberg E.2005. Mikrobiologi Kedokteran.EGC, Jakarta
Kemenkes, RI. (2017). Farmakope Herbal Indonesia. Edisi II. Jakarta : Kemenkes Republik Indonesia. Halaman : 323-32
Published
2022-04-28