Uji Efektivitas GELL Obat Jerawat Dari Ekstrak Etanol Buah Pare (Momordica charantia L.) Terhadap Pertumbuhan Bakteri Propionibacterium acnes
Bacterial infection is a major factor in causing acne. The causes of acne are many (multifactorial), including genetic, endocrine, dietary factors, the activity of the sebaceous glands themselves, psychological factors, mucin, infection by Propionibacterium acne, cosmetics, and other chemicals. Pare extract can be formulated as a gell pimple, which can inhibit the growth of propionibacterium acne. The samples in this study were gell preparations of the ethanol extract of bitter melon with a concentration of 5%, 7.5%, 10%. Based on the results obtained, the addition of the ethanol extract concentration of bitter melon fruit depends on the extract produced. The higher the concentration of gell preparations, the better it is to inhibit bacterial growth. The results showing that pare fruit extract with a concetration of 5%, 7,5%, 10%, and as gell verile 0,025% get a variety of results. And a good resistance zone on the three concentrations that are most close to verile effectiveness is 10% concentration. In conclusion, bitter melon extract can be formulated as an acne medication that can inhibit the growth of the Propionibacterium acnes bacteria.
Harbone, J.B. 1987. Metode Fitokimia Penuntun Cara Modern Menganalisis Ekstrak Tumbuhan. Penerbit ITB. Bandung.
Loveckova, Y and I. Havlikova. 2002. A Microbiological Appoach To Acne Vulgaris. Papers.
Mitsui, T. 1997. New Cosmetic Science. Edisi Kesatu. Amsterdam: Elsevier Science B. V. Kesehatan Universitas Islam Negeri Alauddin Makassar.
Nur Ain Thomas, dkk. 2019. Formulasi dan Uji Efektivitas Gel Ekstrak Buah Pare (Momordica charantia L.) Terhadap Pertumbuhan Bakteri Staphylococcusepidermis dan Propionibacterium acnes Penyebab Jerawat. Jurusan Farmasi. Fakultas Olahraga dan Kesehatan. Universitas Negeri Gorontalo.
WHO. 1992. WHO Ekspert Comite On Ekstrac. WHO technical report series.